预印 简短的报告 版本1 保存在廊下 此版本不是对等审核的

从2006年到2019年对美国兽医教学机构的评估

版本1:收到日期:2020年10月14日/批准日期:2020年10月16日/出版日期:2020年10月16日(CEST 12:05:36)

如何引用:风笛手,b;考尔,k;Kogan l;2006年至2019年美国兽医教学机构受控物质分配评估。预印本2020., 2020100347 (doi: 10.20944/preprints202010.0347.v1)。风笛手,b;考尔,k;Kogan l;2006年至2019年美国兽医教学机构受控物质分配评估。preprints2020, 2020100347 (doi: 10.20944/preprints202010.0347.v1)。

摘要

目的:评价美国附表II和III阿片类药物,巴比妥酸盐和兴奋剂分布变化模式,对美国兽医教育机构。设计:纵向研究。样本:使用时间表II和III药物的兽医教学机构。Procedures: Distribution of controlled substances to veterinary teaching institutions was obtained from the Drug Enforcement Administration’s Automated Reports and Consolidated Orders System (ARCOS) for opioids (e.g. methadone, fentanyl, codeine), barbiturates (pentobarbital, butalbital), and stimulants (amphetamine, methylphenidate, lisdexamfetamine) from 2006 - 2019. Opioids were converted to their morphine milligram equivalents (MME) for evaluation over time. Results: Controlled substance distribution to veterinary schools exhibited dynamic, and agent specific, changes. The total MME for eleven opioids peaked in 2013 and decreased by 17.3% in 2019. Methadone accounted for two-fifths (42.3%) and fentanyl over one-third (35.4%) of the total MME in 2019. Pentobarbital distribution was greatest by weight of all substances studied and peaked in 2011 at 69.4 kg. Stimulants underwent a pronounced decline and were very modest by 2014. Conclusions and Clinical Relevance: Opioids by total MME in veterinary teaching practice have undergone more modest changes than opioids used with humans. Hydrocodone, codeine and recently fentanyl use have declined while methadone increased. Stimulant distribution decreased to become negligible. Together, this pattern of findings warrant continued monitoring.

补充及相关材料

主题领域

阿片类药物;巴比妥酸盐;兴奋剂;兽医;浮动藻属

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